Non cross-linked hyaluronic acid is used successfully in biostimulation of the face, neck, décolleté and hands. Periodic micro-infiltrations are performed so to provide a regenerative stimulus for the tissues. Depending on the face to be treated, the doctor may offer treatments with hyaluronic acid, which are extremely moisturising, or with the addition of amino acids, vitamins, antioxidants, nucleotides, so as to provide other nutrients to the tissue. The treatment protocols then vary with the age of the patient, season and morphology of the face – thereby being able to build real personalised treatment regimes.